Retatrutide

Overview

Retatrutide (LY3437943) is a synthetic modified peptide, sold here as a 10mg vial of lyophilized powder. It is a 39-amino-acid peptide built on a GIP backbone, with a fatty diacid conjugation for extended stability, and is studied in the literature as a combined agonist across the GIP, GLP-1, and glucagon receptors.

Chemical identifiers

Full name	LY3437943 — GIP-backbone peptide with C20 fatty diacid conjugate
Category	Synthetic modified peptide (triple receptor agonist)
CAS number	2381089-83-2
Molecular formula	C221H342N46O68
Molar mass	≈4731.33 g/mol
Sequence	39-residue GIP-derived peptide (Aib2, Aib20, aMeL13 non-coded residues; C20 fatty diacid at position 17 via γ-Glu/AEEA linker)

Source: PubChem CID 171390338.

Molecular structure

Structure diagram not yet added

Studied in the research literature for

General topic areas this compound appears in published preclinical/animal research — not a statement of confirmed outcomes, and not applicable to human use.

Glucose homeostasis and insulin-sensitivity models
Energy expenditure and food-intake regulation studies
Hepatic lipid metabolism models
Combined incretin/glucagon receptor pharmacology research

Storage & handling

Store lyophilized (powder) vials at -20°C, protected from light.
Once reconstituted for laboratory use, keep refrigerated at 2–8°C.
Avoid repeated freeze-thaw cycles, which can degrade peptide integrity.
Handle in accordance with your institution's standard laboratory safety practices.

View this product in the catalog · View Certificate of Analysis

Research use only. This page is provided for laboratory research reference purposes only. It does not constitute medical advice, and nothing on this page should be interpreted as guidance for human or animal use. Products are not evaluated for safety or efficacy in humans.

Overview

Chemical identifiers

Molecular structure

Studied in the research literature for

Storage & handling

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